바이오및뇌공학과 뇌인지 공학 프로그램

세미나

  • home_icon
  • 정보
  • 세미나
Extra Form

ABSTRACT:

Cancer immunotherapy has recently been successful in the treatment of various types of tumors. Cytotoxic lymphocytes, including cytotoxic T lymphocytes (CTLs), natural killer (NK) cells, and gd T cells, play an essential role in elimination of tumors by directly killing tumor cells. Therefore, evaluation of lymphocyte cytotoxicity against tumor cells is critical for the improvement of cancer immunotherapy. Lymphocyte cytotoxicity is a strictly regulated function requiring a multi-step “checkpoint” to minimize normal cell damage. First, cytotoxic lymphocytes migrate to tumor sites and make close contact with tumor cells (trafficking). Second, cytotoxic lymphocytes recognize distinct signatures of tumor cells and make stable contact with tumor cells (recognition). Third, cytotoxic lymphocytes exert cytotoxicity by exocytosis of lytic granules containing cytotoxic molecules, including perforin and granzyme B, to lysis tumor cells (execution). Lastly, cytotoxic lymphocytes successfully performed cytolysis of tumor cells detach from dead cells and re-engage tumor cells to perform further cytotoxicity (detach and re-engage). However, current cytotoxicity assays mostly provide information about final outcomes of cytotoxicity. To overcome this limitation, we are developing new assays that allow “stepwise” evaluation of lymphocyte cytotoxicity using dynamic imaging and microfabrication techniques.

 

* The seminar will be held offline and online[https://kaist.zoom.us/j/89702859664] simultaneously.

 

 

 

 

0329_도준상.jpg

 


  1. [Online ZOOM]_<Starting 4:30 PM , Wednesday, May 4> BBE Department Seminar for Spring Semester 2022

    Date2022.04.28 Byadmin Views1248
    Read More
  2. [Starting 4:30 PM , Wednesday, April 12 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, YongKeun Park

    Date2023.04.06 Byadmin Views530
    Read More
  3. [Starting 4:30 PM , Wednesday, April 26 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, Jangyeon Park

    Date2023.04.13 Byadmin Views453
    Read More
  4. [Starting 4:30 PM , Wednesday, April 5 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, Hyndoo Hwang

    Date2023.03.30 Byadmin Views476
    Read More
  5. [Starting 4:30 PM , Wednesday, August 31 / Venue: YBS Bldg. #207] BBE Department Seminar for Fall Semester 2022

    Date2022.08.26 Byadmin Views680
    Read More
  6. [Starting 4:30 PM , Wednesday, December 07 / Venue: YBS Bldg. #207] BBE Departmental Seminar for Fall Semester 2022

    Date2022.12.07 Byadmin Views753
    Read More
  7. [Starting 4:30 PM , Wednesday, June 7 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, SungMin Son

    Date2023.05.26 Byadmin Views478
    Read More
  8. [Starting 4:30 PM , Wednesday, March 15 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, Sun Kim

    Date2023.03.08 Byadmin Views1085
    Read More
  9. [Starting 4:30 PM , Wednesday, March 22 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, Jongmin Choi

    Date2023.03.16 Byadmin Views874
    Read More
  10. [Starting 4:30 PM , Wednesday, March 29 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, Junsang Doh

    Date2023.03.23 Byadmin Views906
    Read More
  11. [Starting 4:30 PM , Wednesday, March 8 / Venue: YBS Bldg. #207] BBE Departmental Seminar for Spring Semester 2023, Yoonkey Nam

    Date2023.03.06 Byadmin Views729
    Read More
  12. [Starting 4:30 PM , Wednesday, May 17 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023,DaeHee Lee

    Date2023.05.15 Byadmin Views379
    Read More
  13. [Starting 4:30 PM , Wednesday, May 24 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, DongWon Kim

    Date2023.05.15 Byadmin Views341
    Read More
  14. [Starting 4:30 PM , Wednesday, May 3 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, SungJune Kim

    Date2023.04.21 Byadmin Views352
    Read More
  15. [Starting 4:30 PM , Wednesday, November 09 / Venue: YBS Bldg. #207] BBE Departmental Seminar for Fall Semester 2022

    Date2022.11.07 Byadmin Views696
    Read More
  16. [Starting 4:30 PM , Wednesday, November 16 / Venue: YBS Bldg. #207] BBE Departmental Seminar for Fall Semester 2022

    Date2022.11.17 Byadmin Views692
    Read More
  17. [Starting 4:30 PM , Wednesday, November 23 / Venue: YBS Bldg. #207] BBE Departmental Seminar for Fall Semester 2022

    Date2022.11.17 Byadmin Views672
    Read More
  18. [Starting 4:30 PM , Wednesday,October 05 / Venue: YBS Bldg. #207] BBE Departmental Seminar for Fall Semester 2022

    Date2022.10.07 Byadmin Views653
    Read More
  19. [Starting 4:30 PM , Wednesday,October 12 / Venue: YBS Bldg. #207] BBE Departmental Seminar for Fall Semester 2022

    Date2022.10.07 Byadmin Views696
    Read More
  20. [Starting 4:30 PM , Wednesday,October 26 / Venue: YBS Bldg. #207] BBE Departmental Seminar for Fall Semester 2022

    Date2022.10.21 Byadmin Views651
    Read More
Board Pagination Prev 1 2 3 4 5 6 7 8 Next
/ 8