바이오및뇌공학과 뇌인지 공학 프로그램

세미나

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ABSTRACT:

Advanced noninvasive neuroimaging methods provide valuable information on the brain function, but they have obvious pros and cons in terms of temporal and spatial resolution. Functional magnetic resonance imaging (fMRI) using blood-oxygenation-level-dependent (BOLD) effect provides good spatial resolution in the order of millimeters, but has a poor temporal resolution in the order of seconds due to slow hemodynamic responses to neuronal activation, providing indirect information on neuronal activity. In contrast, electroencephalography (EEG) and magnetoencephalography (MEG) provide excellent temporal resolution in the millisecond range, but spatial information is limited to centimeter scales. Therefore, there has been a longstanding demand for noninvasive brain imaging methods capable of detecting neuronal activity at both high temporal and spatial resolution. In this talk, I will introduce a novel approach that enables Direct Imaging of Neuronal Activity (DIANA) using MRI that can dynamically image neuronal spiking activity in milliseconds precision, achieved by data acquisition scheme of rapid 2D line scan synchronized with periodically applied functional stimuli. DIANA was demonstrated through in vivo mouse brain imaging on a 9.4T animal scanner during electrical whisker-pad stimulation. DIANA with milliseconds temporal resolution had high correlations with neuronal spike activities, which could also be applied in capturing the sequential propagation of neuronal activity along the thalamocortical pathway of brain networks. In terms of the contrast mechanism, DIANA was almost unaffected by hemodynamic responses, but was subject to changes in membrane potential-associated tissue relaxation times such as T2 relaxation time. DIANA is expected to break new ground in brain science by providing an in-depth understanding of the hierarchical functional organization of the brain, including the spatiotemporal dynamics of neural networks.

 

* The seminar will be held offline and online[https://kaist.zoom.us/j/89702859664] simultaneously.

 

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  1. [Department Seminar 학과 정기 세미나 안내] (10/11, Wed) Prof. Hirohide Saito

  2. [Department Seminar 학과 정기 세미나 안내] (11/01, Wed) Prof. Hee Chan Kim

  3. [Department Seminar 학과 정기 세미나 안내] (11/08, Wed) Prof. Su-Hyun Kim

  4. [Department Seminar 학과 정기 세미나 안내] (11/15, Wed) Prof. Ain Chung

  5. BBE/BCE Departmental Seminar for Fall Semester 2023

  6. [Department Seminar 학과 정기 세미나 안내] (8/30, Wed) Prof. Kwang-Hyun Cho

  7. [Starting 4:30 PM , Wednesday, May 24 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, DongWon Kim

  8. [Starting 4:30 PM , Wednesday, May 17 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023,DaeHee Lee

  9. [Department Seminar 학과 정기 세미나 안내] (9/13, Wed) Prof. Jaebum Choo

  10. [Starting 4:30 PM , Wednesday, May 3 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, SungJune Kim

  11. [Starting 4:30 PM , Wednesday, June 7 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, SungMin Son

  12. [Starting 4:30 PM , Wednesday, April 26 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, Jangyeon Park

  13. [Department Seminar 학과 정기 세미나 안내] (10/4, Wed) Prof. Hyeon Min Bae

  14. [Starting 4:30 PM , Wednesday, April 12 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, YongKeun Park

  15. [Starting 4:30 PM , Wednesday, April 5 / Venue: YBS Bldg. #207] BCE Departmental Seminar for Spring Semester 2023, Hyndoo Hwang

  16. [Department Seminar 학과 정기 세미나 안내] (11/22, Wed) Prof. Yong Taik Lim

  17. BBE Departmental Seminar for Fall 2022

  18. [Starting 4:30 PM , Wednesday, November 16 / Venue: YBS Bldg. #207] BBE Departmental Seminar for Fall Semester 2022

  19. [Starting 4:30 PM , Wednesday,September 28 / Online ZOOM] BBE Departmental Seminar for Fall Semester 2022

  20. BBE/BCE Departmental Seminar for Spring 2023

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